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Prostacin D Capsule 1 Strip
Tamsulosin Hydrochloride & Dutasteride capsules are used for:
- Managing moderate to severe symptoms of benign prostatic hyperplasia (BPH).
- Reducing the risk of acute urinary retention and the need for surgery in patients with moderate to severe BPH symptoms.
Always take this medication as prescribed by a registered physician.
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✅ Description:
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ How does Prostacin D Capsule work?
This combination drug includes Tamsulosin Hydrochloride, an alpha1A-adrenoreceptor antagonist, and Dutasteride, a dual 5-alpha reductase inhibitor (5ARI). Together, they address both the dynamic and static components of BPH:
- Tamsulosin: Relaxes smooth muscles in the prostate and bladder neck by blocking alpha1A and alpha1D receptors, improving urine flow and reducing symptoms.
- Dutasteride: Inhibits the conversion of testosterone to dihydrotestosterone (DHT), reducing prostate size and addressing the underlying cause of BPH.
✔️ Side Effects of Prostacin D
Impotence, decreased libido, breast disorders (enlargement, tenderness), ejaculation disorders, and dizziness.
✔️ Dosage & Administration of Prostacin D
- Adults (including elderly): Take one capsule (Tamsulosin 0.4 mg + Dutasteride 0.5 mg) orally, 30 minutes after the same meal each day. Swallow the capsule whole; do not chew or open it.
- Renal impairment: No dosage adjustment is needed, but caution is advised for severe cases.
- Hepatic impairment: Use with caution in mild to moderate cases. Contraindicated in severe hepatic impairment.
Always follow a registered physician's advice.
Take Prostacin D with or without food as directed by your physician. Swallow it as a whole with a glass of water. Do not crush, chew, or break it.
✔️ Interactions: Prostacin D
Dutasteride: CYP3A4 inhibitors (e.g., ketoconazole, ritonavir) may increase Dutasteride levels. No significant interactions with Tamsulosin or other drugs like warfarin or digoxin.
Tamsulosin: May enhance hypotensive effects when taken with blood pressure-lowering drugs, PDE5 inhibitors, or other alpha-blockers. Avoid combining with cimetidine or other alpha-blockers.
✔️ Do not use Prostacin D in:
- Women, children, and adolescents.
- Patients are allergic to Dutasteride, Tamsulosin, soya, peanut, or excipients.
- Those with a history of orthostatic hypotension or severe hepatic impairment.
✔️ Pregnancy & Lactation
- Contraindicated for women: Dutasteride may harm a male fetus if exposed during pregnancy. Men on this medication should use condoms if their partner is or could become pregnant.
- Fertility: Dutasteride may reduce sperm count and motility, potentially affecting male fertility.
- Lactation: It is unknown if Tamsulosin or Dutasteride passes into breast milk.
✔️ Precautions & Warnings
- Cardiac failure: A slightly higher risk has been observed with this combination. Monitor patients closely.
- Prostate cancer: Regular PSA testing and digital rectal exams are essential. PSA levels drop by about 50% after 6 months of treatment; establish a new baseline for monitoring.
- Hypotension: Risk of orthostatic hypotension; advise patients to sit or lie down if they feel dizzy.
- Intraoperative Floppy Iris Syndrome (IFIS): May occur during cataract surgery. Discontinue Tamsulosin 1-2 weeks before surgery if possible.
- Breast cancer: Rare cases have been reported in men taking Dutasteride. Patients should report any breast changes, such as lumps or discharge.
✔️ Storage Conditions
Store in a cool, dry place, away from light.
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